منابع مشابه
Influence of atrial fibrillation on microRNA expression
35 Chronic atrial fibrillation (AF) is a complication associated with the dilated atria 36 of patients with valvular heart disease and contributes to worsened pathology. We 37 examined microRNA (miRNA) expression profiles in right and left atrial appendage 38 tissue from valvular heart disease (VHD) patients. Right atrial appendage (RA) from 39 patients undergoing coronary artery bypass graftin...
متن کاملMicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation.
BACKGROUND A characteristic of both clinical and experimental atrial fibrillation (AF) is atrial electric remodeling associated with profound reduction of L-type Ca(2+) current and shortening of the action potential duration. The possibility that microRNAs (miRNAs) may be involved in this process has not been tested. Accordingly, we assessed the potential role of miRNAs in regulating experiment...
متن کاملMicroRNA expression signature in atrial fibrillation with mitral stenosis.
The aim of this study was to investigate the microRNA (miRNA) signature in atrial fibrillation (AF) with mitral stenosis (MS). miRNA arrays were used to evaluate the expression signature of the right atrial appendages of healthy individuals (n=9), patients with MS and AF (n=9) and patients with MS without AF (n=4). The results were validated with qRT-PCR analysis. GOmir was used to predict the ...
متن کاملMicroRNA as a novel player in atrial fibrillation
Atrial fibrillation (AF), with an extremely highly age-dependent prevalence, is a most frequent type of sustained arrhythmia in the clinic both in developing and developed countries (Dobrev and Nattel, 2011). AF patients have a lot of symptoms including palpitations, dizziness, breathlessness, and chest pain. AF will lead to an increased risk of stroke and aggravate congestive heart failure (Sh...
متن کاملProtective effects of simvastatin on atrioventricular node during simulated experimental atrial fibrillation in vitro
Introduction: Recent evidence has indicated that statins can reduce the incidence of both supraventricular and ventricular arrhythmias with various mechanisms. The primary goal of the present study was to determine direct protective role of simvastatin in modifying concealed conduction and the zone of concealment in a simulated model of atrial fibrillation (AF) in an isolated atrioventricula...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical & Experimental Cardiology
سال: 2014
ISSN: 2155-9880
DOI: 10.4172/2155-9880.1000325